Ketamine is a versatile medication originally developed as an anesthetic. It is now recognized for its potential in treating severe depression and other mental health conditions. Unlike traditional antidepressants, which often take weeks to show effects, ketamine can provide rapid relief from symptoms of depression, sometimes with the first treatment.

Ketamine works primarily as an NMDA receptor antagonist, influencing the brain's glutamate system, which plays a role in mood regulation and neural plasticity.

Ketamine does not meet criteria for being physically addictive, though tolerance to its effects may occur with prolonged exposure. If abused, it may pose the risk of being a psychologically addictive substance.

During the first 20 minutes, most patients feel normal. As the treatment continues, you may experience a sense of detachment, altered perceptions such as "floating" or "lightness," and other sensory changes. These feelings will resolve once the treatment is completed.

During a ketamine treatment, you typically won't be fully asleep, but rather in a relaxed, semi-conscious state.

The typical treatment lasts approximately 45 minutes to one hour. Treatments for chronic pain last longer.

You might feel tired or experience a sense of detachment. These sensations will subside 15-20 minutes after the treatment is discontinued.

No. Even if you feel normal after the treatment, ketamine may affect your consciousness. We request that you avoid driving until the following day. Please ensure that you have a friend or family member available to drive you home. For your safety, we cannot allow you to leave the clinic without a driver.

Treatments initially are 2-3 times per week for the first two to three weeks. If patients have a positive outcome, studies show that patients benefit from maintenance treatments, which vary for each individual.

Each treatment costs $600. Payment plans are available.

Outpatient ketamine treatments are not covered by insurance.

Talk therapy can be an ideal way to “lock in” the effects of your ketamine infusions, as your brain is in a unique position where it is open to changing neuropathways. People should continue working with their psychiatrist, psychologist or other behavioral health provider while being treated. We highly encourage individuals to either begin or continue speaking with a qualified therapist. The Vail Clinic is happy to refer you to our network of trusted local therapists.

Frequently Asked Questions